NMR Deconvolution: Quantitative Profiling of Isomeric Mixtures

Lauren S. Lopansri¹, Jacob N. Letson¹, Richard A. O’Brien¹, David R. Battiste¹ and David C. Forbes^1,

¹Department of Chemistry, University of South Alabama, Mobile, AL 36688, USA

Cite this paper

Lauren S. Lopansri, Jacob N. Letson, Richard A. O’Brien, David R. Battiste and David C. Forbes. NMR Deconvolution: Quantitative Profiling of Isomeric Mixtures. World Journal of Chemical Education. 2022; 10(2):51-61. doi: 10.12691/WJCE-10-2-1

Abstract

A method involving NMR band deconvolution has been applied to the instructional/research activities at the undergraduate level. Three case studies are presented to illustrate how unresolved peaks of ¹H and ¹³C NMR spectra can used to obtain quantitative data on isomeric composition. The data generation is rapid and the method can be applied to any organic chemistry laboratory curriculum/research program involving the analysis of NMR spectra. The incorporation of NMR band deconvolutions offers an ideal platform to transition from qualitative to quantitative discernment of NMR data.

Keywords

second-term organic chemistry, isomeric analysis, NMR band deconvolution

Copyright

This work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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